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LBP anticorps

LBP Reactivité: Souris ELISA Hôte: Souris Monoclonal biG33 unconjugated
N° du produit ABIN343173
  • Antigène Voir toutes LBP Anticorps
    LBP (Lipopolysaccharide Binding Protein (LBP))
    Reactivité
    • 40
    • 18
    • 17
    • 9
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    Souris
    Hôte
    • 46
    • 17
    • 5
    • 2
    Souris
    Clonalité
    • 48
    • 22
    Monoclonal
    Conjugué
    • 56
    • 7
    • 3
    • 3
    • 1
    Cet anticorp LBP est non-conjugé
    Application
    • 47
    • 26
    • 24
    • 17
    • 10
    • 9
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA
    Specificité
    Mouse LBP. The antibody blocks LPS binding to membrane bound CD14.
     Réactivité croisée
    Humain, Rat (Rattus)
    Purification
    Protein G affinity column
    Immunogène
    native mouse LBP
    Clone
    BiG33
    Isotype
    IgG1
    Top Product
    Discover our top product LBP Anticorps primaire
  • Indications d'application
    ELISA ,LBP inhibition studies, Western Blot. inhibits binding of LPS to membrane bound CD14, (Inhibits LPS-binding (0.5 ug/ml) to CD14+CHO cells (2 x 106/ml) up to 1:1000, total inhibition 1:5 Binding titre at mouse LBP- ELISA: 1:50.000 Cross reacting with rat LBP
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with bidistilled water
    Concentration
    1 mg/mL
    Buffer
    PBS, pH 7.17
    Agent conservateur
    Without preservative
    Stock
    -20 °C,-80 °C
  • Dziarski, Tapping, Tobias: "Binding of bacterial peptidoglycan to CD14." dans: The Journal of biological chemistry, Vol. 273, Issue 15, pp. 8680-90, (1998) (PubMed).

    Weidemann, Schletter, Dziarski, Kusumoto, Stelter, Rietschel, Flad, Ulmer: "Specific binding of soluble peptidoglycan and muramyldipeptide to CD14 on human monocytes." dans: Infection and immunity, Vol. 65, Issue 3, pp. 858-64, (1997) (PubMed).

  • Antigène
    LBP (Lipopolysaccharide Binding Protein (LBP))
    Autre désignation
    Lipopolysaccharide (LPS)-Binding Protein (LBP) (LBP Produits)
    Synonymes
    anticorps BPIFD2, anticorps Bpifd2, anticorps Ly88, anticorps LPSBP, anticorps LBP, anticorps lipopolysaccharide binding protein, anticorps lipopolysaccharide-binding protein, anticorps LBP, anticorps Lbp, anticorps LOC100472839
    Sujet
    Background: Natural LBP is a 58KD glycoprotein produced in liver. It binds at lipid A of LPS with high affinity (10-9M) and reduced the cellular LPS effects at CD14+ cells (IL1ß, IL6, TNFα). It acts as opsonin for GRAM negative cells, LPS, neutrophiles and granulocytes.
    Poids moléculaire
    ~58kDa
    ID gène
    16803
    UniProt
    Q61805
    Pathways
    Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process
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