Prosaposin anticorps
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- Antigène Voir toutes Prosaposin (PSAP) Anticorps
- Prosaposin (PSAP)
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Prosaposin est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- Specificité
- Reacts with human Saposin-B
- Réactivité croisée (Details)
- May cross react with proteins from other species due to sequence homology
- Purification
- Antiserum
- Immunogène
- Synthetic peptide derived from an internal domain of human PSAP
- Isotype
- IgG
- Top Product
- Discover our top product PSAP Anticorps primaire
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- Indications d'application
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC1:200 - 1:1 000 WB1:500 - 1:5 000 - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Must be reconstituted in distilled water.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- Date de péremption
- 24 months
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- Antigène
- Prosaposin (PSAP)
- Autre désignation
- Proactivator Polypeptide Domain Saposin-B (PSAP) (PSAP Produits)
- Synonymes
- anticorps GLBA, anticorps SAP1, anticorps AI037048, anticorps SGP-1, anticorps SGP1A, anticorps cb759, anticorps wu:fa14a06, anticorps wu:fb36e02, anticorps wu:fb58g07, anticorps PSAP, anticorps PSP-A, anticorps SFTPA1B, anticorps SP-A, anticorps prosaposin, anticorps surfactant protein A1, anticorps PSAP, anticorps Psap, anticorps psap, anticorps LOC100011417, anticorps LOC100304726, anticorps LOC100526719, anticorps SFTPA1
- Sujet
- The lysosomal degradation of sphingolipids takes place by the sequential action of specific hydrolases. Some of these enzymes require specific low-molecular mass, non-enzymic proteins: the sphingolipids activator proteins (coproteins). Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase and galactosylceramide by beta-galactosylceramidase. Saposin-C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, rather than by solubilizing the substrate. Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A, GM1 gangliosides by beta-galactosidase and globotriaosylceramide by alpha-galactosidase A. Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases. Saposin-D is a specific sphingomyelin phosphodiesterase activator.
- ID gène
- 5660
- UniProt
- P07602
- Pathways
- Positive Regulation of Endopeptidase Activity
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