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FAP anticorps (Internal Region)

FAP Reactivité: Souris WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN349584
  • Antigène Voir toutes FAP Anticorps
    FAP (Fibroblast Activation Protein, alpha (FAP))
    Épitope
    • 16
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 66
    • 31
    • 21
    • 13
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 62
    • 11
    Lapin
    Clonalité
    • 61
    • 12
    Polyclonal
    Conjugué
    • 42
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FAP est non-conjugé
    Application
    • 57
    • 23
    • 18
    • 13
    • 13
    • 11
    • 11
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB), ELISA
    Specificité
    This product was affinity purified from monospecific antiserum by immunoaffinity chromatography.  This antibody is known to react with mouse FAP protein.  A BLAST analysis was used to suggest partial cross-reactivity with FAP from human and rat sources based on ~88% homology with the immunizing sequence.    Reactivity with FAP from other sources has not been determined.
    Attributs du produit
    This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. Fibroblast Activation Protein (FAP) is expressed in the stroma of sites that are undergoing wound healing. In addition, it has recently been reported that FAP is expressed in the stroma of sites of metastatic disease. Inhibition of FAP may lead to a dramatic decrease in the number of metastatic osteosarcoma lung nodules. FAP exists as an inactive monomer and when activated forms homodimers or heterodimers with DPP4. Multiple isoforms of FAP are reported as alternative splicing products from a common gene.
    Purification
    purified
    Stérilité
    Sterile filtered
    Immunogène
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of mouse FAP protein.
    Immunogen Type: Peptide
    Isotype
    IgG
    Top Product
    Discover our top product FAP Anticorps primaire
  • Indications d'application
    This affinity purified antibody has been tested for use in ELISA and western blotting.  Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 88 kDa in size corresponding to FAP by western blotting in the appropriate cell lysate or extract.
    Commentaires

    Gene Name: FAP

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.81 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is three (3) months from date of opening.
    Date de péremption
    3 months
  • Antigène
    FAP (Fibroblast Activation Protein, alpha (FAP))
    Autre désignation
    Fibroblast Activation Protein (FAP Produits)
    Synonymes
    anticorps fap-A, anticorps gene 13, anticorps FAP, anticorps fapa, anticorps dppiv, anticorps seprase, anticorps DPPIV, anticorps FAPA, anticorps fibroblast activation protein, anticorps fibroblast activation protein alpha L homeolog, anticorps fibroblast activation protein alpha, anticorps fibroblast activation protein, alpha, anticorps prolyl endopeptidase FAP, anticorps Fap, anticorps fap.L, anticorps FAP, anticorps fap, anticorps LOC100547273
    Sujet
    This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. Fibroblast Activation Protein (FAP)  is expressed in the stroma of sites that are undergoing wound healing. In addition, it has recently been reported that FAP is expressed in the stroma of sites of metastatic disease. Inhibition of FAP may lead to a dramatic decrease in the number of metastatic osteosarcoma lung nodules.  FAP exists as an inactive monomer and when activated forms homodimers or heterodimers with DPP4.  Multiple isoforms of FAP are reported as alternative splicing products from a common gene.
    Synonyms: 170 kDa melanoma membrane bound gelatinase antibody, DPPIV antibody, Integral membrane serine protease antibody, FAPA antibody, Seprase antibody
    ID gène
    14089, 6679749
    UniProt
    P97321
    Pathways
    Tube Formation
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