LGR4 anticorps (Internal Region)

N° du produit ABIN349637

Détail du produit anti-LGR4 anticorps

Antigène: LGR4 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4))

Épitope: Internal Region

Reactivité: Humain, Chimpanzé, Macaque

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LGR4 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: This product was purified from concentrated tissue culture supernate by Protein A chromatography. This antibody is specific for human LGR4 protein. A BLAST analysis was used to suggest cross-reactivity with LGR4 from chimpanzee, orangutan and macaque based on 100% homology with the immunizing sequence. Cross-reactivity with LGR4 from other sources has not been determined.

Réactivité croisée: Chimpanzé, Macaque

Attributs du produit: LGR4, also known as leucine-rich repeat-containing G protein-coupled receptor 4, is a G protein-coupled receptors (GPCRs). GPCRs are membrane bound proteins that play key roles in a variety of physiologic functions. Members of the leucine-rich GPCR (LGR) family, such as GPR48, have multiple N-terminal leucine-rich repeats (LRRs) and a 7-transmembrane domain. LGR4 is an orphan GPCR reported to be expressed in steroidogenic tissues such as placenta, ovary, testis, adrenal, pancreas, prostate, and thyroid, as well as in spinal cord, stomach, heart, and kidney.

Purification: purified

Stérilité: Sterile filtered

Immunogène: This monoclonal antibody was produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human LGR4 protein. The hybridoma was produced by fusing BALB/c mouse splenocytes and mouse myeloma SP2/O cells using conventional technology.
Immunogen Type: Peptide

Clone: 6G8-B3-G5-C3

Isotype: IgG2b kappa

Information d'application

Indications d'application: This monoclonal antibody is suitable for ELISA, immunohistochemistry and western blotting. Expect a band approximately 102 kDa in size corresponding to LGR4 protein by western blotting in the appropriate cell lysate or extract. Specific conditions for reactivity should be optimized by the end user. Use formalin-fixed paraffin-embedded sections for immunohistochemistry. No pre-treatment of sample is required.

Commentaires:

Gene Name: LGR4

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.13 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is three (3) months from date of opening.

Date de péremption: 3 months

Références pour anticorps anti-LGR4 (ABIN349637)

Yi, Xiong, Gong, Bellister, Ellis, Liu: "Analysis of LGR4 receptor distribution in human and mouse tissues." dans: PLoS ONE, Vol. 8, Issue 10, pp. e78144, (2014) (PubMed).

Détails sur LGR4

Antigène: LGR4 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4))

Autre désignation: LGR4 (LGR4 Produits)

Synonymes: anticorps BNMD17, anticorps GPR48, anticorps 9130225G07, anticorps A330106J01Rik, anticorps A930009A08Rik, anticorps Gpr48, anticorps leucine rich repeat containing G protein-coupled receptor 4, anticorps leucine-rich repeat-containing G protein-coupled receptor 4, anticorps LGR4, anticorps Lgr4

Sujet: LGR4, also known as leucine-rich repeat-containing G protein-coupled receptor 4, is a G protein-coupled receptors (GPCRs). GPCRs are membrane bound proteins that play key roles in a variety of physiologic functions. Members of the leucine-rich GPCR (LGR) family, such as GPR48, have multiple N-terminal leucine-rich repeats (LRRs) and a 7-transmembrane domain. LGR4 is an orphan GPCR reported to be expressed in steroidogenic tissues such as placenta, ovary, testis, adrenal, pancreas, prostate, and thyroid, as well as in spinal cord, stomach, heart, and kidney.
Synonyms: LGR4 leucine-rich repeat-containing G protein-coupled receptor 4

ID gène: 55366, 157694513

UniProt: Q8N537