UBE2J2 anticorps (Internal Region)

N° du produit ABIN349639

Détail du produit anti-UBE2J2 anticorps

Antigène: UBE2J2 (Ubiquitin-Conjugating Enzyme E2, J2 (UBE2J2))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2J2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Specificité: This affinity purified antibody is directed against human Ube2j2 protein. The product was affinity purified from monospecific antiserum by immunoaffinity chromatography. A BLAST analysis was used to suggest cross-reactivity with Ube2j2 protein from human, horse, opossum, cattle, dog, mouse, rat, macaque, salmon, chicken, zebra finch, Xenopus and platypus based on 100% homology with the immunizing sequence. Reactivity against homologues from other sources is not known.

Réactivité croisée: Souris, Rat (Rattus)

Attributs du produit: This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. Ube2j2 and Ube2j1 are homologs of the yeast ubiquitin-conjugating enzyme UBC6, which catalyzes the covalent attachment of ubiquitin to other proteins. These proteins constitute a distinct family of ubiquitin-conjugating enzymes sharing a conserved non-canonical active site sequence and a C-terminal trans-membrane domain. By analogy with yeast UBC6, Ube2j1 and Ube2j2 are localized to the endoplasmic reticulum and seem to function in the selective degradation of misfolded membrane proteins and in general mediation of the stress response.

Immunogène: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of the human Ube2j2 protein.
Immunogen Type: Peptide

Isotype: IgG

Information d'application

Indications d'application: This affinity purified antibody has been tested for use in ELISA, western blotting and immunoprecipitation. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 29 kDa in size corresponding to Ube2j2 protein by western blotting in the appropriate cell lysate or extract.

Commentaires:

Gene Name: UBE2J2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.64 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store secondary antibody 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is three (3) months from date of opening.

Date de péremption: 3 months

Détails sur UBE2J2

Antigène: UBE2J2 (Ubiquitin-Conjugating Enzyme E2, J2 (UBE2J2))

Abstract: UBE2J2 Produits

Synonymes: anticorps NCUBE-2, anticorps NCUBE2, anticorps PRO2121, anticorps 1200007B18Rik, anticorps 2400008G19Rik, anticorps 5730472G04Rik, anticorps AL022923, anticorps Ubc6, anticorps Ubc6p, anticorps zgc:162164, anticorps ubiquitin conjugating enzyme E2 J2, anticorps ubiquitin-conjugating enzyme E2J 2, anticorps ubiquitin-conjugating enzyme E2, J2, anticorps ubiquitin-conjugating enzyme E2 J2, anticorps ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast), anticorps ubiquitin conjugating enzyme E2 J2 L homeolog, anticorps UBE2J2, anticorps Ube2j2, anticorps LOC5574000, anticorps CpipJ_CPIJ008956, anticorps ube2j2, anticorps uce2, anticorps ube2j2.L, anticorps LOC100067387

Sujet: This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. Ube2j2 and Ube2j1 are homologs of the yeast ubiquitin-conjugating enzyme UBC6, which catalyzes the covalent attachment of ubiquitin to other proteins. These proteins constitute a distinct family of ubiquitin-conjugating enzymes sharing a conserved non-canonical active site sequence and a C-terminal trans-membrane domain. By analogy with yeast UBC6, Ube2j1 and Ube2j2 are localized to the endoplasmic reticulum and seem to function in the selective degradation of misfolded membrane proteins and in general mediation of the stress response.
Synonyms: Ubiquitin-conjugating enzyme E2 J2 Non-canonical ubiquitin-conjugating enzyme 2 Ube2j2

ID gène: 118424, 251757431

UniProt: Q8N2K1