A synthetic peptide from the internal region of human Activating molecule in BECN1 regulated autophagy protein 1 (AMBRA1, AMRA1) conjugated to an immunogenic carrier protein has been used as the immunogen. The antigen is homologous in mouse.
Isotype
IgG
Indications d'application
IHC, WB. Use at a concentration of 10-50 μg,ml. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
Conseil sur la manipulation
Avoid freeze and thaw cycles.
Stock
4 °C/-20 °C
Stockage commentaire
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Date de péremption
12 months
Antigène
AMRA1
Sujet
Function: Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation. Subcellular location: Cytoplasmic vesicle âÄ° autophagosome,Mammalian Autophagy,Activating molecule in BECN1-regulated autophagy protein 1, AMBRA1, AMRA1