A synthetic peptide from the n-terminal region of human Axonal membrane protein GAP-43 (Neuromodulin, growth-associated protein 43) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat, mouse, zebra fish and chicken.
IHC. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
Conseil sur la manipulation
Avoid freeze and thaw cycles.
Stock
4 °C/-20 °C
Stockage commentaire
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
FUNCTION: This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons. SUBUNIT: Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence. SUBCELLULAR LOCATION: Cell membrane, Peripheral membrane protein, Cytoplasmic side. Cell projection, growth cone membrane, Peripheral membrane protein, Cytoplasmic side. Cell junction, synapse. Note: Cytoplasmic surface of growth cone and synaptic plasma membranes.,Neuronal,Neuromodulin, growth-associated protein 43, protein F1, Basp2, B-50