CHMP3 anticorps (N-Term)

N° du produit ABIN350226

Détail du produit anti-CHMP3 anticorps

Antigène: CHMP3 (Charged Multivesicular Body Protein 3 (CHMP3))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHMP3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: Specific for CHMP3.

Réactivité croisée: Humain, Souris, Rat

Réactivité croisée (Details): Other species not yet tested.

Purification: IgG

Immunogène: A synthetic peptide from the n-terminal of human VPS24 conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in rat and mouse.

Isotype: IgG

Information d'application

Indications d'application: IHC, WB. Use at a concentration of 10-50 μg,ml. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur CHMP3

Antigène: CHMP3 (Charged Multivesicular Body Protein 3 (CHMP3))

Autre désignation: VPS24 (CHMP3 Produits)

Synonymes: anticorps CG9779, anticorps Dmel\\CG9779, anticorps Vps24, anticorps dvps24, anticorps vps24, anticorps VPS24, anticorps CHMP3, anticorps GB15107, anticorps wu:fb47g01, anticorps zgc:76972, anticorps NEDF, anticorps 25.1, anticorps 4921505F14Rik, anticorps 9130011K15Rik, anticorps CGI-49, anticorps D6Ertd286e, anticorps Vacuolar protein sorting 24, anticorps charged multivesicular body protein 3, anticorps SNF7 family protein, anticorps hypothetical protein, anticorps neuroendocrine differentiation factor, putative, anticorps charged multivesicular body protein 3 S homeolog, anticorps Vps24, anticorps chmp3, anticorps VPS24.2, anticorps CpipJ_CPIJ004098, anticorps PGTG_02107, anticorps LOC5569267, anticorps Smp_032150, anticorps CHMP3, anticorps LOC410607, anticorps Chmp3, anticorps chmp3.S

Sujet: FUNCTION: Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. Required for sorting/trafficking of EGF receptor. In case of infection, the HIV-1 virus takes advantage of the ESCRT-III complex for budding and exocytic cargos of viral proteins. SUBCELLULAR LOCATION: Cytoplasm, cytosol. Membrane, Lipid-anchor. TISSUE SPECIFICITY: Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.,Vesicle Protein Sorting,Chromatin-modifying protein 3, Vacuolar protein-sorting-associated protein 24, hVps24, Neuroendocrine differentiation factor, Charged multivesicular body protein 3, NEDF

UniProt: Q9Y3E7