CHMP6 anticorps (C-Term)

N° du produit ABIN350233

Détail du produit anti-CHMP6 anticorps

Antigène: CHMP6 (Charged Multivesicular Body Protein 6 (CHMP6))

Épitope: C-Term

Reactivité: Souris

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp CHMP6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: Specific for CHMP6.

Réactivité croisée: Souris, Rat

Réactivité croisée (Details): Other species not yet tested.

Purification: IgG

Immunogène: A synthetic peptide from the c-terminal region of mouse CHMP6 conjugated to an immunogenic carrier protein was used as the antigen. The peptide shares 95% identity with rat's.

Isotype: IgG

Information d'application

Indications d'application: IHC, WB. Use at a concentration of 10-50 μg,ml. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur CHMP6

Antigène: CHMP6 (Charged Multivesicular Body Protein 6 (CHMP6))

Autre désignation: CHMP6 (CHMP6 Produits)

Synonymes: anticorps chmp6, anticorps vps20, anticorps 2400004G01Rik, anticorps VPS20, anticorps RGD1565325, anticorps chmp6l, anticorps flj11749l, anticorps wu:fb79d02, anticorps zgc:110067, anticorps charged multivesicular body protein 6, anticorps charged multivesicular body protein 6 L homeolog, anticorps charged multivesicular body protein 6 S homeolog, anticorps charged multivesicular body protein 6b, anticorps LOC100280982, anticorps chmp6.L, anticorps chmp6.S, anticorps CHMP6, anticorps chmp6, anticorps Tsp_08316, anticorps Chmp6, anticorps chmp6b

Sujet: FUNCTION: Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. In the ESCRT-III complex, it probably serves as an acceptor for ESCRT-II complex on endosomal membranes. SUBUNIT: Component of the endosomal sorting required for transport complex III (ESCRT-III), at least composed of CHMP1A, CHMP1B, CHMP2A, CHMP2B, CHMP3/VPS24, CHMP4A/SHAX2, CHMP4B/SHAX1, CHMP4C/SHAX3, CHMP5/SNF7DC2 and CHMP6/VPS20. In the complex, it interacts directly with CHMP4A, CHMP4B and CHMP4C. Interacts directly with SNF8, VPS25 and VPS36 components of the ESCRT-II complex. SUBCELLULAR LOCATION: Intracytoplasmic membrane. Endosome membrane, Lipid-anchor . Note: Localizes to endosomal membranes.,Vesicle Protein Sorting,Charged multivesicular body protein 6, Chromatin-modifying protein 6

UniProt: P0C0A3