Dynactin 1 anticorps (AA 120-170)
-
- Antigène Voir toutes Dynactin 1 (DCTN1) Anticorps
- Dynactin 1 (DCTN1)
-
Épitope
- AA 120-170
-
Reactivité
- Humain
-
Hôte
-
Mouton
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp Dynactin 1 est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificité
- Specific for DCTN1.
- Réactivité croisée
- Humain, Souris, Rat
- Réactivité croisée (Details)
- Other species not yet tested.
- Purification
- IgG
- Immunogène
- A synthetic peptide from AA 120-170 of human DCTN1 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat and moue.
- Isotype
- IgG
- Top Product
- Discover our top product DCTN1 Anticorps primaire
-
-
- Indications d'application
- IHC, WB. Use at a concentration of 10-50 μg,ml. The optimal dilution should be determined by the end user. Not yet tested in other applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
- Conseil sur la manipulation
- Avoid freeze and thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- Date de péremption
- 12 months
-
- Antigène
- Dynactin 1 (DCTN1)
- Autre désignation
- DCTN1 (DCTN1 Produits)
- Synonymes
-
anticorps DAP-150, anticorps DP-150, anticorps P135, anticorps Chip150, anticorps DCTN1, anticorps DKFZp469C1813, anticorps AL022633, anticorps Glued, anticorps p150, anticorps p150
, anticorps CG9206, anticorps DYNA_DROME, anticorps Dmel\\CG9206, anticorps FCP-D, anticorps Glu, anticorps P150, anticorps P150[Glued], anticorps p150/Glued, anticorps p150/glued, anticorps p150[Glued], anticorps p150[glued], anticorps t1, anticorps Dynactin-1, anticorps glued, anticorps dynactin subunit 1, anticorps dynactin 1, anticorps Dynactin 1, p150 subunit, anticorps dynactin subunit 1 L homeolog, anticorps DCTN1, anticorps Dctn1, anticorps DCTN1-p150, anticorps dctn1.L - Sujet
- FUNCTION: Required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein-dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles. SUBUNIT: Large macromolecular complex of at least 10 components, p150(glued) binds directly to microtubules and to cytoplasmic dynein. Interacts with the C-terminus of MAPRE1, MAPRE2 and MAPRE3. SUBCELLULAR LOCATION: Cytoplasm. Cytoplasm, cytoskeleton. TISSUE SPECIFICITY: Brain. DISEASE: Defects in DCTN1 are the cause of progressive lower motor neuron disease. PLMND is a progressive dominant disease that has no sensory symptoms.,Signal Transduction,DAP-150, DP-150, p150-glued,p135, Dynactin subunit 1, 150 kDa dynein-associated polypeptide
- UniProt
- Q14203
- Pathways
- M Phase, ER-Nucleus Signaling
-