BDNF anticorps (N-Term)
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- Antigène Voir toutes BDNF Anticorps
- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
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Épitope
- N-Term
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Reactivité
- Humain, Rat, Souris
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Hôte
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Mouton
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BDNF est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificité
- Specific for mature BDNF.
- Purification
- Affinity purified
- Immunogène
- A synthetic peptide from n-terminal region of human mature BDNF (Brain derived neurotrophic factor) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in many other species including rat, mouse, zebra fish and xenopus.
- Top Product
- Discover our top product BDNF Anticorps primaire
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- Indications d'application
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A concentration of 1-5 µg/ml is recommended.
The optimal concentration should be determined by the end user.
Not yet tested in other applications. - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- Conseil sur la manipulation
- Avoid freeze and thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
- Abstract
- BDNF Produits
- Synonymes
- anticorps ANON2, anticorps BULN2, anticorps bdnf-A, anticorps BDNF, anticorps bdnf, anticorps brain derived neurotrophic factor, anticorps brain-derived neurotrophic factor, anticorps brain-derived neurotrophic factor L homeolog, anticorps brain-derived neurotrophic factor S homeolog, anticorps BDNF, anticorps Bdnf, anticorps bdnf, anticorps bdnf.L, anticorps bdnf.S
- Sujet
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Function: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
Subunit: Monomers and homodimers. Binds to NTRK2/TRKB.
Subcellular location: Secreted. Also known as: Brain-derived neurotrophic factor, BDNF, Abrineurin. - Pathways
- Signalisation RTK, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
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