A synthetic peptide from the c-terminal of human Synaptotagmin 12 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat, mouse.
SYT12
Reactivité: Humain
WB, IF (cc), IF (p)
Hôte: Lapin
Polyclonal
AbBy Fluor® 350
Indications d'application
A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Conseil sur la manipulation
Avoid freeze and thaw cycles.
Stock
4 °C/-20 °C
Stockage commentaire
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Function: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane, Single-pass membrane protein. Also known as: Synaptotagmin-12, SYT12, SYT-12, Synaptotagmin XII, SytXII.