Tyrosinase-Related Protein 1 anticorps (4th Cytoplasmic Loop)
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- Antigène Voir toutes Tyrosinase-Related Protein 1 (TYRP1) Anticorps
- Tyrosinase-Related Protein 1 (TYRP1)
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Épitope
- 4th Cytoplasmic Loop
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Reactivité
- Drosophila melanogaster
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Tyrosinase-Related Protein 1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificité
- Specific for TRP.
- Réactivité croisée
- Drosophila melanogaster
- Réactivité croisée (Details)
- Other species not yet tested.
- Purification
- IgG
- Immunogène
- A synthetic peptide from 4th cytoplasmic loop of drosophila TRP (Transient receptor potential protein) conjugated to an immunogenic carrier protein was used as the antigen.
- Isotype
- IgG
- Top Product
- Discover our top product TYRP1 Anticorps primaire
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- Indications d'application
- IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
- Conseil sur la manipulation
- Avoid freeze and thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- Tyrosinase-Related Protein 1 (TYRP1)
- Autre désignation
- TRP (TYRP1 Produits)
- Synonymes
- anticorps CAS2, anticorps CATB, anticorps GP75, anticorps OCA3, anticorps TRP, anticorps TRP1, anticorps TYRP, anticorps b-PROTEIN, anticorps LOC397853, anticorps Trypsin, anticorps hm:zeh0659, anticorps tyrp1, anticorps zgc:100893, anticorps B, anticorps TYRP1, anticorps tyrp-1, anticorps TRP-1, anticorps Tyrp, anticorps b, anticorps brown, anticorps isa, anticorps tyrosinase related protein 1, anticorps protease, serine 1 L homeolog, anticorps tyrosinase-related protein 1b, anticorps tyrosinase-related protein 1, anticorps tyrosinase-related protein 1 L homeolog, anticorps tyrosinase-related protein 1a, anticorps TYRP1, anticorps prss1.L, anticorps tyrp1b, anticorps Tyrp1, anticorps tyrp1.L, anticorps tyrp1, anticorps LOC100136490, anticorps tyrp-1, anticorps tyrp1a
- Sujet
- FUNCTION: A light-sensitive calcium channel that is required for inositide-mediated Ca(2+) entry in the retina during phospholipase C (PLC)-mediated phototransduction. Ca(2+) influx may then feed back and inhibit PLC, thereby facilitating phosphatidylinositol 4,5 bisphosphate (PIP2) recycling. Trp and trpl act together in the light response, though it is unclear whether as heteromultimers or as distinct units, and are activated by fatty acids and metabolic stress. Also required for olfactory adaptation and may be involved in olfactory system development. SUBUNIT: The C-terminus interacts with a PDZ domain of inaD to form the core of the inaD signaling complex. Other members of the complex include norpA (PLC), inaC (PKC), and possibly trpl, ninaC, FKBP59, calmodulin and rhodopsin. Forms homomultimers and heteromultimers with trpl. Interaction with trpl is mediated in part by the N-terminal region and the transmembrane domains. Also interacts, though to a lower extent, with trp-gamma. SUBCELLULAR LOCATION: Membrane, Multi-pass membrane protein. Note: Localized on plasma membrane loops found at the base of the rhabdomere, in close proximity to the calcium stores. TISSUE SPECIFICITY: Expressed predominantly in the rhabdomeres of photoreceptor cells. Expressed in the third antennal segment and in the olfactory segment at approximately 70 hours after puparium formation during antennal development.,Drosophila TRP,Transient receptor potential cation channel protein
- UniProt
- P19334
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