VAMP2 anticorps (AA 10-60)

N° du produit ABIN351358

Détail du produit anti-VAMP2 anticorps

Antigène: VAMP2 (Vesicle-Associated Membrane Protein 2 (Synaptobrevin 2) (VAMP2))

Épitope: AA 10-60

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VAMP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: Specific for VAMP2 and VAMP1.

Réactivité croisée: Humain, Souris, Rat

Réactivité croisée (Details): Other species not yet tested.

Purification: IgG

Immunogène: A synthetic peptide from AA 10-60 of human VAMP2 conjugated to blue carrier protein was used as the antigen. The VAMP2 peptide shares 93% shared identity with VAMP1. The peptide is homologous in many other species including rat, mouse and xenopus.

Isotype: IgG

Information d'application

Indications d'application: IHC, WB. A working concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur VAMP2

Antigène: VAMP2 (Vesicle-Associated Membrane Protein 2 (Synaptobrevin 2) (VAMP2))

Autre désignation: VAMP 2 (VAMP2 Produits)

Synonymes: anticorps zgc:73302, anticorps wu:fj61c06, anticorps VAMP2, anticorps vamp2-a, anticorps xsybi, anticorps Syb-2, anticorps Syb2, anticorps sybII, anticorps RATVAMPB, anticorps RATVAMPIR, anticorps SYB, anticorps SYB2, anticorps VAMP-2, anticorps syb2, anticorps vamp2, anticorps xsybii, anticorps vesicle-associated membrane protein 2, anticorps vesicle associated membrane protein 2, anticorps vesicle associated membrane protein 2 S homeolog, anticorps vesicle-associated membrane protein 2 (synaptobrevin 2), anticorps vesicle associated membrane protein 2 L homeolog, anticorps vamp2, anticorps VAMP2, anticorps vamp2.S, anticorps Vamp2, anticorps vamp2.L

Sujet: The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. FUNCTION: Involved in the targeting and/or fusion of transport vesicles to their target membrane. SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane, Single-pass type IV membrane protein. Cell junction, synapse, synaptosome. Note: Neuronal synaptic vesicles.,Vesicle Transport,VAMP-2, Synaptobrevin-2, VAMP2, SYB2. VAMP1, Synaptobrevin-1

UniProt: P63027

Pathways: Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport