KDM3B anticorps (N-Term)
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- Antigène Voir toutes KDM3B Anticorps
- KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))
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Épitope
- N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp KDM3B est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody will recognize JMJD1B (N-term).
- Purification
- Protein A Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human JMJD1B.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product KDM3B Anticorps primaire
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- Indications d'application
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ELISA: 1/1,000. Western Blot: 1/250-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Antigène
- KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))
- Autre désignation
- JMJD1B / KDM3B (KDM3B Produits)
- Synonymes
- anticorps KDM3B, anticorps JMJD1B, anticorps 5830462I21Rik, anticorps JHDM2B, anticorps Jmjd1b, anticorps mKIAA1082, anticorps 5qNCA, anticorps C5orf7, anticorps NET22, anticorps lysine demethylase 3B, anticorps lysine (K)-specific demethylase 3B, anticorps lysine-specific demethylase 3B, anticorps KDM3B lysine (K)-specific demethylase 3B, anticorps KDM3B, anticorps LOC100540242, anticorps kdm3b, anticorps Kdm3b
- Sujet
- Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.Synonyms: 5qNCA, C5orf7, JHDM2B, JmjC domain-containing histone demethylation protein 2B, Jumonji domain-containing protein 1B, KIAA1082, Lysine-specific demethylase 3B, Nuclear protein 5qNCA
- ID gène
- 51780, 9606
- UniProt
- Q7LBC6
- Pathways
- L'effet Warburg
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