Cadherin 8 anticorps (N-Term)

N° du produit ABIN356866

Détail du produit anti-Cadherin 8 anticorps

Antigène: Cadherin 8 (CDH8)

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cadherin 8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody is specific to CDH8 (N-term).

Purification: Protein A Chromatography followed by Peptide Affinity purification.

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human CDH8.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Références pour anticorps anti-Cadherin 8 (ABIN356866)

Kher, Sha, Escobar, Andreoli, Wang, Xu, Wandinger-Ness, Bacallao: "Ectopic expression of cadherin 8 is sufficient to cause cyst formation in a novel 3D collagen matrix renal tubule culture." dans: American journal of physiology. Cell physiology, Vol. 301, Issue 1, pp. C99-C105, (2011) (PubMed).

Détails sur Cadherin 8

Antigène: Cadherin 8 (CDH8)

Autre désignation: Cadherin-8 (CDH8 Produits)

Synonymes: anticorps AI851472, anticorps cad8, anticorps cadherin-8, anticorps Nbla04261, anticorps cadherin 8, anticorps cadherin 8, type 2, anticorps Cdh8, anticorps CDH8

Sujet: CDH8 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.Synonyms: CDH8

ID gène: 1006, 9606

UniProt: P55286

Pathways: Cell-Cell Junction Organization