CDH6 anticorps (C-Term)

N° du produit ABIN356890

Détail du produit anti-CDH6 anticorps

Antigène: CDH6 (K-Cadherin (CDH6))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDH6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects K Cadherin at C-term.

Purification: Protein A column, followed by peptide affinity purification.

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CDH6.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 10 - 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Détails sur CDH6

Antigène: CDH6 (K-Cadherin (CDH6))

Autre désignation: Cadherin-6 (CDH6 Produits)

Synonymes: anticorps KCAD, anticorps K-cadherin, anticorps cad6, anticorps cadherin-6, anticorps CAD6, anticorps c-cad6B, anticorps cadherin 6, anticorps Cdh6, anticorps CDH6

Sujet: CDH6 is a type II classical cadherin from the cadherin superfamily. It is a calcium dependent cell-cell adhesion membrane glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of the CDH6 gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion.Synonyms: CDH6, Cadherin K, K-Cadherin, Kidney cadherin

Poids moléculaire: 88309 Da

ID gène: 1004, 9606

UniProt: P55285

Pathways: Cell-Cell Junction Organization