ALPL anticorps (N-Term)
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- Antigène Voir toutes ALPL Anticorps
- ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))
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Épitope
- N-Term
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ALPL est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody detects Alkaline Phosphatase at N-term.
- Purification
- Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human ALPL.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product ALPL Anticorps primaire
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- Indications d'application
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ELISA 1: 1,000. Western blot 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- Antigène
- ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))
- Autre désignation
- Alkaline Phosphatase / ALPL (ALPL Produits)
- Synonymes
- anticorps ALP, anticorps iap, anticorps alpl, anticorps AP-TNAP, anticorps APTNAP, anticorps HOPS, anticorps TNAP, anticorps TNSALP, anticorps Akp-2, anticorps Akp2, anticorps PHOA, anticorps TNS-AP, anticorps alkaline phosphatase, liver/bone/kidney L homeolog, anticorps alkaline phosphatase, liver/bone/kidney, anticorps alkaline phosphatase, intestinal, gene 2, anticorps alkaline phosphatase, liver/bone/kidney pseudogene, anticorps alpl.L, anticorps ALPL, anticorps alpi.2, anticorps LOC100031702, anticorps Alpl
- Sujet
- There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The genes for the first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. This protein is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization, however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to a disorder known as hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms.Synonyms: AP-TNAP, Alkaline phosphatase, Alkaline phosphatase liver/bone/kidney isozyme, TNSALP, tissue-nonspecific isozyme
- Poids moléculaire
- 57323 Da
- ID gène
- 249, 9606
- UniProt
- P05186
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