GJA8 anticorps (C-Term)

N° du produit ABIN357099

Détail du produit anti-GJA8 anticorps

Antigène: GJA8 (Gap Junction Protein, alpha 8, 50kDa (GJA8))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GJA8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects Connexin 50 (GJA8) at C-term.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human GJA8.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Détails sur GJA8

Antigène: GJA8 (Gap Junction Protein, alpha 8, 50kDa (GJA8))

Autre désignation: GJA8 / Cx50 (GJA8 Produits)

Synonymes: anticorps Aey5, anticorps Cnx50, anticorps Cx50, anticorps Lop10, anticorps CAE, anticorps CAE1, anticorps CTRCT1, anticorps CX50, anticorps CZP1, anticorps MP70, anticorps Cx45.6, anticorps gap junction protein, alpha 8, anticorps gap junction protein alpha 8, anticorps Gja8, anticorps GJA8

Sujet: GJA8 is a an integral membrane protein that belongs to the connexin family, alpha-type (group II) subfamily. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins. This particular connexin only forms junctional channels. GJA8 is expressed in the eye lens, and defects in GJA8 are the cause of zonular pulverulent cataract type 1 (CZP1), a form of autosomal dominant congenital cataract.Synonyms: Connexin-50, Gap junction alpha-8 protein, Lens fiber protein MP70

Poids moléculaire: 48097 Da

ID gène: 2703, 9606

UniProt: P48165