SIGLEC9 anticorps (C-Term)

N° du produit ABIN357151

Détail du produit anti-SIGLEC9 anticorps

Antigène: SIGLEC9 (Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIGLEC9 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects SIGLEC9 at C-term.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human SIGLEC9.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Détails sur SIGLEC9

Antigène: SIGLEC9 (Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9))

Autre désignation: CD329 / SIGLEC9 (SIGLEC9 Produits)

Synonymes: anticorps CD329, anticorps CDw329, anticorps FOAP-9, anticorps OBBP-LIKE, anticorps siglec-9, anticorps siglec9, anticorps sialic acid binding Ig like lectin 9, anticorps sialic acid-binding immunoglobulin-like lectin 9, anticorps SIGLEC9

Sujet: SIGLEC9 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. This protein is expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils). It is found in liver, fetal liver, bone marrow, placenta, spleen and in lower levels in skeletal muscle, fetal brain, stomach, lung, thymus, prostate, brain, mammary, adrenal gland, colon, trachea, cerebellum, testis, small intestine and spinal cordon. SIGLEC9 contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.Synonyms: CDw329, FOAP-9, OBBP-like, SIGLEC-9, Sialic acid-binding Ig-like lectin 9

Poids moléculaire: 50081 Da

ID gène: 27180

NCBI Accession: NP_055256

UniProt: Q9Y336