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USP4 anticorps (C-Term)

USP4 Reactivité: Humain WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN357526
  • Antigène Voir toutes USP4 Anticorps
    USP4 (Ubiquitin Specific Peptidase 4 (USP4))
    Épitope
    • 15
    • 10
    • 9
    • 8
    • 8
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 49
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 47
    • 1
    • 1
    Lapin
    Clonalité
    • 48
    • 1
    Polyclonal
    Conjugué
    • 23
    • 6
    • 6
    • 6
    • 4
    • 4
    Cet anticorp USP4 est non-conjugé
    Application
    • 35
    • 34
    • 31
    • 6
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody is specific to USP4 (C-term).
    Purification
    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogène
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human USP4.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product USP4 Anticorps primaire
  • Indications d'application
    ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène
    USP4 (Ubiquitin Specific Peptidase 4 (USP4))
    Autre désignation
    USP4 / UNP (USP4 Produits)
    Synonymes
    anticorps UNP, anticorps Unph, anticorps F730026I20Rik, anticorps Unp, anticorps mKIAA4155, anticorps ubiquitin specific peptidase 4, anticorps ubiquitin specific peptidase 4 (proto-oncogene), anticorps USP4, anticorps Usp4
    Sujet
    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.Synonyms: Deubiquitinating enzyme 4, UNPH, Ubiquitin carboxyl-terminal hydrolase 4, Ubiquitin thioesterase 4, Ubiquitin-specific-processing protease 4, Ubiquitous nuclear protein homolog
    Poids moléculaire
    108564 Da
    ID gène
    7375, 5874
    UniProt
    Q13107
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