USP13 anticorps (Middle Region)

N° du produit ABIN357545

Détail du produit anti-USP13 anticorps

Antigène: USP13 (Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13))

Épitope: Middle Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP13 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody is specific to USP13 (Center).

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human USP13.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur USP13

Antigène: USP13 (Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13))

Autre désignation: USP13 (USP13 Produits)

Synonymes: anticorps ISOT3, anticorps IsoT-3, anticorps 2700071E21Rik, anticorps AI848077, anticorps usp13, anticorps MGC163140, anticorps ubiquitin specific peptidase 13, anticorps ubiquitin specific peptidase 13 (isopeptidase T-3), anticorps ubiquitin carboxyl-terminal hydrolase 13, anticorps universal stress protein, anticorps USP13, anticorps Usp13, anticorps usp13, anticorps MGYG_01656, anticorps RR_RS02895

Sujet: Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.Synonyms: Deubiquitinating enzyme 13, ISOT-3, ISOT3, Isopeptidase T-3, Ubiquitin carboxyl-terminal hydrolase 13, Ubiquitin thioesterase 13, Ubiquitin-specific-processing protease 13

Poids moléculaire: 97299 Da

ID gène: 8975, 5874

UniProt: Q92995

Pathways: SARS-CoV-2 Protein Interactome