PML anticorps (Sumoylation Site)
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- Antigène Voir toutes PML Anticorps
- PML (Promyelocytic Leukemia (PML))
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Épitope
- Sumoylation Site
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PML est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificité
- This antibody is specific to PML (Sumoylation Site).
- Purification
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Immunogène
- This antibody is generated from rabbits immunized with the KLH conjugated synthetic peptide PRKVIKMESEEGKEA containing a predicted sumoylation site from the central region of human PML.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product PML Anticorps primaire
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- Indications d'application
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ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Antigène
- PML (Promyelocytic Leukemia (PML))
- Autre désignation
- PML / RNF71 (PML Produits)
- Synonymes
- anticorps MYL, anticorps PP8675, anticorps RNF71, anticorps TRIM19, anticorps 1200009E24Rik, anticorps AI661194, anticorps Trim19, anticorps RGD1562602, anticorps PML, anticorps promyelocytic leukemia, anticorps PML, anticorps Pml
- Sujet
- PML is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL).Synonyms: MYL, Probable transcription factor PML, RING finger protein 71, TRIM19, Tripartite motif-containing protein 19
- Poids moléculaire
- 97516 Da
- ID gène
- 5371, 9606
- UniProt
- P29590
- Pathways
- Signalisation p53, Retinoic Acid Receptor Signaling Pathway, Maintenance of Protein Location, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus
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