M6PR
Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye, Lapin
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
ELISA: 1/1,000. Immunohistochemistry: 1/10-1/50. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium Azide as preservative.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Ohka, Tan, Ishiyama, Ogasawara, Hanasaka, Ishida, Hagiwara, Liu, Chong, Hanaki, Schiavo: "The uncoating of EV71 in mature late endosomes requires CD-M6PR." dans: Biology open, Vol. 11, Issue 9, (2022) (PubMed).
M6PR is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.Synonyms: 46 kDa mannose 6-phosphate receptor, CD Man-6-P receptor, CD-MPR, Cation-dependent mannose-6-phosphate receptor, MPR46, MPRD