CDK2 anticorps (pThr160)
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- Antigène Voir toutes CDK2 Anticorps
- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
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Épitope
- pThr160
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CDK2 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody detects CDK2 pThr160. Predicted to cross react with Mouse (100 % Antigen Homology).
- Purification
- Protein G Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T160 of human Cdk2.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product CDK2 Anticorps primaire
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- Indications d'application
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ELISA: 1/1,000. Western Blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Antigène
- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
- Autre désignation
- CDK2 (CDK2 Produits)
- Synonymes
- anticorps p33(CDK2), anticorps A630093N05Rik, anticorps wu:fa10c02, anticorps zgc:56598, anticorps zgc:77684, anticorps eg1, anticorps CDKN2, anticorps cdk2L, anticorps cyclin dependent kinase 2, anticorps cyclin-dependent kinase 2, anticorps cyclin-dependent kinase 2 S homeolog, anticorps CDK2, anticorps Cdk2, anticorps cdk2, anticorps cdk2.S
- Sujet
- Cdk2 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.Synonyms: Cell division protein kinase 2, Cyclin dependent kinase 2, p33 protein kinase
- Poids moléculaire
- 39038 Da
- ID gène
- 1017, 9606
- UniProt
- P24941
- Pathways
- Signalisation PI3K-Akt, Cycle Cellulaire, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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