ANTXR1 anticorps (pTyr382)
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- Antigène Voir toutes ANTXR1 Anticorps
- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
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Épitope
- pTyr382
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ANTXR1 est non-conjugé
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Application
- Enzyme Immunoassay (EIA)
- Specificité
- This antibody detects Anthrax Toxin Receptor 1 (ANTXR1) pTyr382. Predicted to cross react with Mouse (100 % Antigen Homology).
- Purification
- Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
- Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y382 of human ANTXR1.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product ANTXR1 Anticorps primaire
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- Indications d'application
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ELISA: 1/1,000. Dot Blot: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Antigène
- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
- Autre désignation
- Anthrax Toxin Receptor 1 (ANTXR1 Produits)
- Synonymes
- anticorps ANTXR1, anticorps ATR, anticorps TEM8, anticorps 2310008J16Rik, anticorps 2810405N18Rik, anticorps Antrx1, anticorps Tem8, anticorps anthrax toxin receptor 1, anticorps ANTXR1, anticorps Antxr1
- Sujet
- ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.Synonyms: ANTXR1, ATR, TEM8, Tumor endothelial marker 8
- Poids moléculaire
- 62789 Da
- ID gène
- 84168, 9606
- UniProt
- Q9H6X2
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