Sclerostin anticorps (Middle Region)
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- Antigène Voir toutes Sclerostin (SOST) Anticorps
- Sclerostin (SOST)
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Épitope
- AA 141-171, Middle Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Sclerostin est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificité
- This antibody recognizes SOST (Center).
- Purification
- Protein A Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- Immunogène
- KLH conjugated synthetic peptide between 141~171 amino acids from the Center region of Human SOST.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product SOST Anticorps primaire
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- Indications d'application
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ELISA: 1/1,000. Western Blot: 1/50-1/100Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Antigène
- Sclerostin (SOST)
- Autre désignation
- Sclerostin / SOST (SOST Produits)
- Synonymes
- anticorps LOC100313724, anticorps CDD, anticorps VBCH, anticorps 5430411E23Rik, anticorps sclerostin, anticorps LOC100313724, anticorps SOST, anticorps Sost
- Sujet
- Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of the sclerostin gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.
- ID gène
- 50964, 9606
- UniProt
- Q9BQB4
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