ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/10 - 1/50. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
anticorps zfyve11, anticorps fyve-dsp2, anticorps FYVE-DSP2, anticorps ZFYVE11, anticorps AA596759, anticorps ESTM44, anticorps mKIAA0647, anticorps myotubularin related protein 4, anticorps myotubularin related protein 4 L homeolog, anticorps Mtmr4, anticorps MTMR4, anticorps mtmr4, anticorps mtmr4.L
Sujet
MTMR, a member of the myotubularin family, encodes an intracellular protein of 1,195 amino acids, and shares approximately 47 % sequence identity with MTMR3, spiking to over 70 % identity in the catalytic domain and the double zinc finger (FYVE) motif. PCR analysis detects expression of MTMR4 in all human tissues examined except lung, small intestine, stomach, salivary gland, adrenal gland, and uterus. Subcellular localization of MTMR4 in transfected HeLa cells showed a perinuclear distribution, similar to that seen with MTMR3. MTMR4 dephosphorylates para-nitrophenylphosphate and phosphatidylinositol 3-phosphate.Synonyms: FYVE domain-containing dual specificity protein phosphatase 2, KIAA0647, Myotubularin-related protein 4, ZFYVE11, Zinc finger FYVE domain-containing protein 11