CERK anticorps (C-Term)
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- Antigène Voir toutes CERK Anticorps
- CERK (Ceramide Kinase (CERK))
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Épitope
- C-Term
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CERK est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody reacts to CERK.
- Purification
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CERK.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product CERK Anticorps primaire
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- Indications d'application
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Antigène
- CERK (Ceramide Kinase (CERK))
- Autre désignation
- Ceramide Kinase (CERK Produits)
- Synonymes
- anticorps AI848610, anticorps D330016D08Rik, anticorps mKIAA1646, anticorps LK4, anticorps dA59H18.2, anticorps dA59H18.3, anticorps hCERK, anticorps CERK, anticorps si:ch211-162i19.1, anticorps MGC81777, anticorps CG16708, anticorps DCERK, anticorps Dcerk, anticorps Dmel\\CG16708, anticorps dcerk, anticorps ceramide kinase, anticorps ceramide kinase S homeolog, anticorps Ceramide kinase, anticorps Cerk, anticorps CERK, anticorps cerk, anticorps cerk.S, anticorps CpipJ_CPIJ003342, anticorps LOAG_11245, anticorps LOC5579301, anticorps Bm1_50005
- Sujet
- Ceramide kinases convert the sphingolipid metabolite ceramide into ceramide-1-phosphate, both key mediators of cellular apoptosis and survival. Ceramide metabolism plays an essential role in the viability of neuronal cells, the membranes of which are particularly rich in sphingolipids. CERK catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. This enzyme acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8 dihydroceramide), and to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. High level expression is noted in heart, brain, skeletal muscle, kidney and liver, moderate expression in peripheral blood leukocytes and thymus, and low expression in spleen, small intestine, placenta and lung.Synonyms: Acylsphingosine kinase, KIAA1646, LK4, Lipid kinase 4, hCERK
- ID gène
- 64781, 9606
- UniProt
- Q8TCT0
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