MAP3K12 anticorps (C-Term)

N° du produit ABIN359408

Détail du produit anti-MAP3K12 anticorps

Antigène: MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP3K12 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects MAP3K12 at C-term.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ZPK.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Détails sur MAP3K12

Antigène: MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))

Autre désignation: MAP3K12 (MAP3K12 Produits)

Synonymes: anticorps DLK, anticorps MEKK12, anticorps MUK, anticorps ZPK, anticorps ZPKP1, anticorps PK, anticorps Zpk, anticorps zgc:77370, anticorps MGC151798, anticorps dlk, anticorps map3k12, anticorps map3k12a, anticorps mekk12, anticorps muk, anticorps zpk, anticorps zpkp1, anticorps DKFZp459K2433, anticorps map3k12-a, anticorps map3k12-b, anticorps map3k12b, anticorps mitogen-activated protein kinase kinase kinase 12, anticorps mitogen activated protein kinase kinase kinase 12, anticorps mitogen-activated protein kinase kinase kinase 12 S homeolog, anticorps mitogen-activated protein kinase kinase kinase 12 L homeolog, anticorps MAP3K12, anticorps Map3k12, anticorps map3k12, anticorps map3k12.S, anticorps map3k12.L

Sujet: ZPK is a member of serine/threonine protein kinase family. This kinase contains a leucine-zipper domain, and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation.Synonyms: Dual leucine zipper bearing kinase, Leucine-zipper protein kinase, MAPK-upstream kinase, Mitogen-activated protein kinase kinase kinase 12, Mixed lineage kinase

Poids moléculaire: 93188 Da

ID gène: 7786, 9606

UniProt: Q12852

Pathways: Signalisation MAPK