PLK2 anticorps (C-Term)

N° du produit ABIN359469

Détail du produit anti-PLK2 anticorps

Antigène: PLK2 (Polo-Like Kinase 2 (PLK2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLK2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects PLK2 (SNK) at C-term.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human SNK.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA 1: 1,000. Western blot 1: 100 - 1-500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Détails sur PLK2

Antigène: PLK2 (Polo-Like Kinase 2 (PLK2))

Autre désignation: PLK2 / SNK (PLK2 Produits)

Synonymes: anticorps SNK, anticorps hPlk2, anticorps hSNK, anticorps Snk, anticorps PLK2, anticorps Plx2, anticorps MGC53990, anticorps plk2, anticorps zgc:165644, anticorps polo like kinase 2, anticorps polo-like kinase 2, anticorps polo-like kinase 2 L homeolog, anticorps polo-like kinase 2b (Drosophila), anticorps Serine/threonine-protein kinase plk-2, anticorps PLK2, anticorps Plk2, anticorps plk2.L, anticorps plk2b, anticorps plk2, anticorps plk-2

Sujet: Plks (polo-like kinases) encode serine/threonine kinases that are closelyrelated to polo and CDC5, genes that are required for passage through mitosisin Drosophila and Saccharomyces, respectively. Polo-like kinases, whichinclude Plk, Snk (for serum-inducible kinase, also designated Plk2) and Fnk(for FGF-inducible kinase, also designated Plk3 or PRK), play a role in cellproliferation. Plk protein accumulates in the cell during S and G2 phases ofthe cell cycle, and both protein content and catalytic activity peak at theonset of mitosis, followed by a rapid reduction after mitosis. Snk and Fnk areimmediate-early response genes that are first expressed during G1 phase. SNK may play a role in the division of at least some cell types, such as fibroblasts, and could function in embryogenesis, wound healing or neoplasia SNK mRNA is rapidly induced in human lung fibroblasts upon reintroduction of serum following 36 hours of serum deprivation.Synonyms: PLK-2, Polo-like kinase 2, Serine/threonine-protein kinase PLK2, Serine/threonine-protein kinase SNK, Serum-inducible kinase

Poids moléculaire: 78236 Da

ID gène: 10769, 9606

UniProt: Q9NYY3