TNK2 anticorps (C-Term)

N° du produit ABIN359970

Détail du produit anti-TNK2 anticorps

Antigène: TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNK2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to ACK1.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ACK1.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western Blot: 1/10 - 1/50. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur TNK2

Antigène: TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))

Autre désignation: TNK2 / ACK1 (TNK2 Produits)

Synonymes: anticorps ACK, anticorps ACK-1, anticorps ACK1, anticorps p21cdc42Hs, anticorps AW552477, anticorps Ack, anticorps Cdgip, anticorps Pyk1, anticorps ack1, anticorps ackb, anticorps tnk2, anticorps tnk2b, anticorps wu:fj16g04, anticorps zgc:154019, anticorps tyrosine kinase non receptor 2, anticorps tyrosine kinase, non-receptor, 2, anticorps tyrosine kinase, non-receptor, 1, anticorps TNK2, anticorps Tnk2, anticorps tnk1

Sujet: ACK1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.Synonyms: Activated CDC42 kinase 1

ID gène: 10188, 9606

UniProt: Q07912