CYP2R1
Reactivité: Humain, Souris, Rat, Singe, Porc, Chien, Cheval, Poisson zèbre (Danio rerio), Roussette (Chauve-souris)
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Antigène
CYP2R1
(Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1))
anticorps cytochrome P450 family 2 subfamily R member 1, anticorps cytochrome P450, family 2, subfamily R, polypeptide 1, anticorps cytochrome P450, family 2, subfamily r, polypeptide 1, anticorps CYP2R1, anticorps cyp2r1, anticorps Cyp2r1
Sujet
CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in CYP2R1 gene has been associated with selective 25-hydroxyvitamin D deficiency.Synonyms: Cytochrome P450 2R1, Vitamin D 25-hydroxylase