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ALOX5AP anticorps (AA 94-124)

ALOX5AP Reactivité: Humain WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN360268
  • Antigène Voir toutes ALOX5AP Anticorps
    ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))
    Épitope
    • 3
    • 1
    • 1
    • 1
    AA 94-124
    Reactivité
    • 14
    • 2
    • 1
    Humain
    Hôte
    • 12
    • 3
    Lapin
    Clonalité
    • 14
    • 1
    Polyclonal
    Conjugué
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ALOX5AP est non-conjugé
    Application
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody recognizes ALOX5AP.
    Cellular Localization: Nucleus membrane. Endoplasmic reticulum membrane.
    Purification
    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
    Immunogène
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94~124 amino acids selected from the Center region of Human ALOX5AP. Genename: ALOX5AP
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ALOX5AP Anticorps primaire
  • Indications d'application
    ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène
    ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))
    Autre désignation
    ALOX5AP / FLAP (ALOX5AP Produits)
    Synonymes
    anticorps fj65d02, anticorps zgc:63982, anticorps wu:fj65d02, anticorps flap, anticorps al5ap, anticorps Alox5ap, anticorps ALOX5AP, anticorps Flap, anticorps FLAP, anticorps arachidonate 5-lipoxygenase-activating protein, anticorps arachidonate 5-lipoxygenase activating protein, anticorps alox5ap, anticorps ALOX5AP, anticorps Alox5ap
    Sujet
    Genetic variations in ALOX5AP may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:601367], also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors. Note=Genetic variations in ALOX5AP may be associated with susceptibility to myocardial infarction. Involvement in myocardial infarction is however unclear: according to some authors (PubMed:14770184), a 4-SNP haplotype in ALOX5AP confers risk of myocardial infarction, while according to other (PubMed:17304054) ALOX5AP is not implicated in this condition. Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.Synonyms: Arachidonate 5-lipoxygenase-activating protein, MK-886-binding protein
    ID gène
    241, 9606
    UniProt
    P20292
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