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PKN3 anticorps (C-Term)

PKN3 Reactivité: Humain WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN360331
  • Antigène Voir toutes PKN3 Anticorps
    PKN3 (Protein Kinase N3 (PKN3))
    Épitope
    • 13
    • 8
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    C-Term
    Reactivité
    • 26
    • 22
    • 1
    Humain
    Hôte
    • 37
    • 2
    Lapin
    Clonalité
    • 39
    Polyclonal
    Conjugué
    • 13
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PKN3 est non-conjugé
    Application
    • 29
    • 25
    • 9
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to PKN beta.
    Purification
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogène
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PKN beta.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PKN3 Anticorps primaire
  • Indications d'application
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/10 - 1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène
    PKN3 (Protein Kinase N3 (PKN3))
    Autre désignation
    PKN3 (PKN3 Produits)
    Synonymes
    anticorps prkcl2, anticorps wu:fb92a02, anticorps si:dkey-202g15.3, anticorps PKN3, anticorps RP11-545E17.1, anticorps AW209115, anticorps BC034126, anticorps LRRGT00147, anticorps protein kinase N3, anticorps pkn3, anticorps PKN3, anticorps Pkn3
    Sujet
    PKN3, a protein kinase C-related molecule, mediates malignant cell growth downstream of activated PI3K. PKN3 is required for invasive prostate cell growth as assessed by 3D cell culture assays and in an orthotopic mouse tumor model by inducible expression of short hairpin RNA (shRNA). PKN3 is regulated by PI3K at both the expression level and the catalytic activity level. Therefore, PKN3 might represent a preferred target for therapeutic intervention in cancers that lack tumor suppressor PTEN function or depend on chronic activation of PI3K.Synonyms: PKN beta, PKN-beta, PKNBETA, Protein-kinase C-related kinase 3, Serine/threonine-protein kinase N3
    ID gène
    29941, 9606
    UniProt
    Q6P5Z2
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