DUSP8 anticorps (C-Term)

N° du produit ABIN360785

Détail du produit anti-DUSP8 anticorps

Antigène: DUSP8 (Dual Specificity Phosphatase 8 (DUSP8))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUSP8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to DUSP8.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human DUSP8.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur DUSP8

Antigène: DUSP8 (Dual Specificity Phosphatase 8 (DUSP8))

Abstract: DUSP8 Produits

Synonymes: anticorps zgc:77593, anticorps C11orf81, anticorps HB5, anticorps HVH-5, anticorps HVH8, anticorps 5530400B01Rik, anticorps AI593498, anticorps Nttp1, anticorps Hb5, anticorps M3/6, anticorps DUSP8, anticorps dual specificity phosphatase 8, anticorps dual specificity phosphatase 8a, anticorps dual specificity protein phosphatase 8, anticorps DUSP8, anticorps dusp8, anticorps dusp8a, anticorps DSP8, anticorps Dusp8, anticorps LOC615727

Sujet: DUSP8 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP8 inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin.Synonyms: Dual specificity protein phosphatase 8

ID gène: 1850, 9606

UniProt: Q13202