DUSP14 anticorps (C-Term)

N° du produit ABIN360795

Détail du produit anti-DUSP14 anticorps

Antigène: DUSP14 (Dual Specificity Phosphatase 14 (DUSP14))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUSP14 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to DUSP14.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human DUSP14.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur DUSP14

Antigène: DUSP14 (Dual Specificity Phosphatase 14 (DUSP14))

Autre désignation: DUSP14 / MKP6 (DUSP14 Produits)

Synonymes: anticorps MGC84083, anticorps zgc:101746, anticorps DUSP14, anticorps mkp-l, anticorps mkp6, anticorps MKP-L, anticorps MKP6, anticorps 1110014C10Rik, anticorps 2310042C07Rik, anticorps D11Ertd395e, anticorps Mkp6, anticorps dual specificity phosphatase 14, anticorps dual specificity phosphatase 14 L homeolog, anticorps DUSP14, anticorps dusp14.L, anticorps dusp14, anticorps Dusp14

Sujet: DUSP14 is involved in the inactivation of MAP kinases. This proein dephosphorylates ERK, JNK and p38 MAP-kinases. In addition to antigen recognition by the T-cell receptor, T-cell activation requires a second signal from a costimulatory receptor, such as CD28, which interacts with B7-1 (CD80) and B7-2 (CD86) ligands on antigen-presenting cells. CD28 costimulation induces transcription of interleukin-2 and stabilizes newly synthesized IL2 through the activation of mitogen-activated protein kinases (MAPKs), such as ERK and JNK, and the subsequent creation of AP1 transcription factor. DUSP14 is a negative regulator of CD28 signaling.Synonyms: Dual specificity protein phosphatase 14, MAP kinase phosphatase 6, MKP-1-like protein tyrosine phosphatase, Mitogen-activated protein kinase phosphatase 6

ID gène: 11072, 9606

UniProt: O95147