IL20RA anticorps (Extracellular Domain)

N° du produit ABIN360917

Détail du produit anti-IL20RA anticorps

Antigène: IL20RA (Interleukin 20 Receptor alpha (IL20RA))

Épitope: Extracellular Domain

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL20RA est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects IL-20Ralpha.

Purification: Protein A/G affinity chromatography

Immunogène: Recombinant protein of IL-20Ralpha extracellular domain.

Clone: 11C42

Isotype: IgG2

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IL20RA

Antigène: IL20RA (Interleukin 20 Receptor alpha (IL20RA))

Autre désignation: IL20RA (IL20RA Produits)

Synonymes: anticorps CRF2-8, anticorps IL-20R-alpha, anticorps IL-20R1, anticorps IL-20RA, anticorps E230031K19, anticorps interleukin 20 receptor subunit alpha, anticorps interleukin 20 receptor, alpha, anticorps IL20RA, anticorps Il20ra

Sujet: The receptor for interleukin 20 is a heterodimer of 2 orphan class II cytokine receptor subunits, IL20RA, also called ZCYTOR7, and IL20RB, also called DIRS1. Binding assays demonstrated that IL20 bound to BHK transfectants expressing both IL20RA and IL20RB, but not to untransfected cells nor to transfectants expressing either receptor subunit alone. Binding of (125)I labeled IL20 was eliminated in the presence of 100 fold excess of unlabeled IL20 but not in the presence of 100 fold excess of the unrelated cytokine, IL21. The binding data revealed 88,000 IL20 receptors per cell, with a binding affinity of approximately 1.5 nM. Both receptor subunits were expressed in skin and were dramatically upregulated in psoriatic skin.Synonyms: Cytokine receptor class-II member 8, Cytokine receptor family 2 member 8, IL-20R-alpha, IL-20R1, Interleukin-20 receptor alpha chain, ZCYTOR7

ID gène: 237313

NCBI Accession: NP_766374

UniProt: Q6PHB0