Retinoid X Receptor beta anticorps

N° du produit ABIN361387

Détail du produit anti-Retinoid X Receptor beta anticorps

Antigène: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Retinoid X Receptor beta est non-conjugé

Application: Western Blotting (WB)

Specificité: Specific for the ~48k RXR-( protein.

Réactivité croisée: Souris, Rat (Rattus)

Purification: Protein G purified culture supernatant

Immunogène: Synthetic peptide corresponding to amino acid residues from the hinge region conjugated to KLH

Clone: 147

Isotype: IgG1

Information d'application

Indications d'application: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Stock: -20 °C

Détails sur Retinoid X Receptor beta

Antigène: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Autre désignation: RXRB (RXRB Produits)

Sujet: Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXRa, ß and (), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005). Anti-Human Retinoid X Receptor Antibody, (-Isotype Western blot of hippocampal lysate showing specific immunolabeling of the ~48k RXR-ß protein.

Poids moléculaire: '48 kDa

ID gène: 6257

UniProt: P28702

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway