RPS6KA2 anticorps (C-Term)

N° du produit ABIN361520

Détail du produit anti-RPS6KA2 anticorps

Antigène: RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))

Épitope: C-Term

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPS6KA2 est non-conjugé

Application: Western Blotting (WB)

Specificité: Specific for the ~90k RSK2 protein.

Réactivité croisée: Humain

Homologie: bovine, canine, chicken, mouse, rat

Purification: Antigen Affinity Purified from Pooled Serum

Immunogène: Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH

Information d'application

Indications d'application: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Stock: -20 °C

Références pour anticorps anti-RPS6KA2 (ABIN361520)

Hegde, Capell, Ibrahim, Klett, Patel, Sougiannis, Kelly: "Phosphodiesterase 11A (PDE11A), Enriched in Ventral Hippocampus Neurons, is Required for Consolidation of Social but not Nonsocial Memories in Mice." dans: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 41, Issue 12, pp. 2920-2931, (2017) (PubMed).

Détails sur RPS6KA2

Antigène: RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))

Autre désignation: RPS6KA2 (RPS6KA2 Produits)

Synonymes: anticorps HU-2, anticorps MAPKAPK1C, anticorps RSK, anticorps RSK3, anticorps S6K-alpha, anticorps S6K-alpha2, anticorps p90-RSK3, anticorps pp90RSK3, anticorps 90kDa, anticorps D17Wsu134e, anticorps Rps6ka-rs1, anticorps Rsk3, anticorps p90rsk, anticorps pp90rsk, anticorps ribosomal protein S6 kinase A2, anticorps ribosomal protein S6 kinase, polypeptide 2, anticorps Rps6ka2, anticorps RPS6KA2

Sujet: The p90 ribosomal S6 kinases (RSK)1–4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin–Lowry syndrome, which is characterized by mental retardation and growth deficits (Hanauer and Young, 2002). Recent work suggests that RSK2 exerts a tonic regulation on G-protein coupled signaling (Sheffler et al., 2006). Anti-Ribosomal S6 Kinase Western blot of rat hippocampal lysate showing specific immunolabeling of the ~90k RSK2 protein.

Poids moléculaire: '90 kDa

ID gène: 20112

UniProt: Q9WUT3

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Activation of Innate immune Response, Toll-Like Receptors Cascades