SOD1 anticorps

N° du produit ABIN361646

Détail du produit anti-SOD1 anticorps

Antigène: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOD1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Specificité: Detects ~23 kDa (human) and ~19 kDa (other species).

Réactivité croisée: Corail, Boeuf (Vache), Chien, Poisson, Hamster, Humain, Invertébré, Mollusca, Singe, Souris, Porc, Lapin, Rat, Mouton, Xenopus laevis

Purification: Protein A Purified

Immunogène: Synthetic Human Cu/Zn SOD Peptide

Information d'application

Indications d'application:

• WB (1:5000)
• IHC (1:100)
• optimal dilutions for assays should be determined by the user.

Commentaires:

0.2 μg/ml of ABIN361645 was sufficient for detection of Cu/Zn SOD in 20 μg of HeLa cell lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:AP as the secondary antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.0, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C

Références pour anticorps anti-SOD1 (ABIN361646)

Leung, Wang, Mak, Ng, Leung: "Differential proteomic responses in hepatopancreas and adductor muscles of the green-lipped mussel Perna viridis to stresses induced by cadmium and hydrogen peroxide." dans: Aquatic toxicology (Amsterdam, Netherlands), Vol. 105, Issue 1-2, pp. 49-61, (2011) (PubMed).

Wong, Leung, Djurisić, Leung: "Toxicities of nano zinc oxide to five marine organisms: influences of aggregate size and ion solubility." dans: Analytical and bioanalytical chemistry, Vol. 396, Issue 2, pp. 609-18, (2010) (PubMed).

Ho, Hsu, Yang, Lee, Chien: "Sialic acid reduces acute endotoxemia-induced liver dysfunction in the rat." dans: Shock (Augusta, Ga.), Vol. 32, Issue 2, pp. 228-35, (2009) (PubMed).

Wu, Hsiao, Chien, Lai: "Ischemic conditioning by short periods of reperfusion attenuates renal ischemia/reperfusion induced apoptosis and autophagy in the rat." dans: Journal of biomedical science, Vol. 16, pp. 19, (2009) (PubMed).

Lahaie-Collins, Bournival, Plouffe, Carange, Martinoli: "Sesamin modulates tyrosine hydroxylase, superoxide dismutase, catalase, inducible NO synthase and interleukin-6 expression in dopaminergic cells under MPP+-induced oxidative stress." dans: Oxidative medicine and cellular longevity, Vol. 1, Issue 1, pp. 54-62, (2009) (PubMed).

Détails sur SOD1

Antigène: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Autre désignation: SOD1 (SOD1 Produits)

Synonymes: anticorps LOC692639, anticorps ALS, anticorps ALS1, anticorps IPOA, anticorps SOD, anticorps hSod1, anticorps homodimer, anticorps CG11793, anticorps Cu, anticorps Cu-Zn SOD, anticorps Cu/Zn SOD, anticorps Cu/Zn sod, anticorps Cu/Zn superoxide dismutase, anticorps Cu/ZnSOD, anticorps CuSOD, anticorps CuZn SOD, anticorps CuZn-SOD, anticorps CuZn-SOD1, anticorps CuZnSOD, anticorps Cu[2+]/Zn[2+]SOD, anticorps Dmel\\CG11793, anticorps G, anticorps Mn SOD, anticorps SOD-1, anticorps SOD1, anticorps Sod-1, anticorps Sod1, anticorps To, anticorps To-1, anticorps Zn SOD, anticorps Zn Sod, anticorps Zn-SOD, anticorps ZnSod, anticorps cSOD, anticorps cSod, anticorps dSOD1, anticorps l(3)108, anticorps l(3)68Af', anticorps l(3)G, anticorps sod, anticorps sod1, anticorps CU/ZN-SOD, anticorps SODC, anticorps DKFZP469M1833, anticorps B430204E11Rik, anticorps Cu/Zn-SOD, anticorps Ipo-1, anticorps Ipo1, anticorps SOD1L1, anticorps XSODB, anticorps als, anticorps als1, anticorps ipoa, anticorps sod1-a, anticorps ZSOD, anticorps cuzn, anticorps Cu/Zn superoxide dismutase, anticorps superoxide dismutase 1, anticorps Superoxide dismutase 1, anticorps superoxide dismutase 1, soluble, anticorps superoxide dismutase 1 S homeolog, anticorps Superoxide dismutase [Cu-Zn], anticorps superoxide dismutase 1 L homeolog, anticorps superoxide dismutase [Cu-Zn]-like, anticorps superoxide dismutase [Cu-Zn], anticorps superoxide dismutase Sod1, anticorps SOD, anticorps SOD1, anticorps Sod1, anticorps sod1, anticorps sod1.S, anticorps sod-1, anticorps sod1.L, anticorps LOC101451855, anticorps LOC101115136

Sujet: Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body (3). It works by catalyzing the dismutation of the superoxide radical O2ˉ to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase (2,5). In general, SODs play a major role in antioxidant defense mechanisms (4). There are two main types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge (3). The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form (SOD3 or EC-SOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDA and it exists only in the extra-cellular space (7). SOD3 can also be distinguished by its heparin-binding capacity (1).

ID gène: 6647

NCBI Accession: NP_000445

UniProt: P00441

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis