AHSA1 anticorps

N° du produit ABIN361854

Détail du produit anti-AHSA1 anticorps

Antigène: AHSA1 (Activator of HSP90 ATPase Activity 1 (AHSA1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AHSA1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: Detects ~ 38 kDa.

Réactivité croisée: Humain, Souris, Rat

Purification: Protein A Purified

Immunogène: Recombinant Full Length Mouse Aha1 Protein

Information d'application

Indications d'application:

• WB (1:1000)
• ICC/IF (1:60)
• optimal dilutions for assays should be determined by the user.

Commentaires:

1 μl/ml of ABIN361853 was sufficient for detection of Aha1 in 10 μg of mixed human cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C

Références pour anticorps anti-AHSA1 (ABIN361854)

Echeverría, Bernthaler, Dupuis, Mayer, Picard: "An interaction network predicted from public data as a discovery tool: application to the Hsp90 molecular chaperone machine." dans: PLoS ONE, Vol. 6, Issue 10, pp. e26044, (2011) (PubMed).

Détails sur AHSA1

Antigène: AHSA1 (Activator of HSP90 ATPase Activity 1 (AHSA1))

Autre désignation: AHA1 (AHSA1 Produits)

Synonymes: anticorps ahsa1, anticorps MGC52884, anticorps MGC132147, anticorps MGC80312, anticorps AHSA1, anticorps MGC89589, anticorps wu:fb83b05, anticorps zgc:136821, anticorps zgc:56075, anticorps AHA1, anticorps C14orf3, anticorps p38, anticorps BC023857, anticorps AHA1, activator of heat shock 90kDa protein ATPase homolog 1 S homeolog, anticorps activator of Hsp90 ATPase activity 1, anticorps AHA1, activator of heat shock 90kDa protein ATPase homolog 1 L homeolog, anticorps activator of HSP90 ATPase activity 1, anticorps AHA1, activator of heat shock 90kDa protein ATPase homolog 1, anticorps AHA1, activator of heat shock protein ATPase homolog 1a, anticorps AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast), anticorps AHA1, activator of heat shock protein ATPase 1, anticorps ahsa1.S, anticorps AHSA1, anticorps ahsa1.L, anticorps ahsa1, anticorps ahsa1a, anticorps Ahsa1

Sujet: Aha1 is a member of the HSP90 cochaperone family, and is thought to stimulate HSP90 ATPase activity by competing with p23 and other co-chaperones for HSP90 binding (1, 2). It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G) (3). Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors (4).

ID gène: 217737

NCBI Accession: NP_666148

UniProt: Q8BK64