VASP anticorps (pSer157)
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- Antigène Voir toutes VASP Anticorps
- VASP (Vasodilator-Stimulated phosphoprotein (VASP))
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Épitope
- pSer157
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp VASP est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificité
- The antibody detects endogenous level of VASP only when phosphorylated at serine 157.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
- Immunogène
- Peptide sequence around phosphorylation site of pSer157 (R-V-S (p) -N-A) derived from Human VASP. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Isotype
- IgG
- Top Product
- Discover our top product VASP Anticorps primaire
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- Indications d'application
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Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Antigène
- VASP (Vasodilator-Stimulated phosphoprotein (VASP))
- Autre désignation
- VASP (VASP Produits)
- Synonymes
- anticorps vasp, anticorps MGC80889, anticorps wu:fb23b04, anticorps wu:fk84g05, anticorps zgc:110347, anticorps si:dkey-113g17.1, anticorps si:ch211-202c21.1, anticorps DDBDRAFT_0188463, anticorps DDBDRAFT_0229340, anticorps DDB_0188463, anticorps DDB_0229340, anticorps VASP, anticorps vasodilator stimulated phosphoprotein S homeolog, anticorps vasodilator stimulated phosphoprotein b, anticorps protein enabled, anticorps vasodilator-stimulated phosphoprotein, anticorps vasodilator stimulated phosphoprotein a, anticorps vasodilator stimulated phosphoprotein, anticorps vasp.S, anticorps vaspb, anticorps LOC5573842, anticorps CpipJ_CPIJ004706, anticorps CpipJ_CPIJ004707, anticorps vasP, anticorps vasp, anticorps VASP, anticorps vaspa, anticorps Vasp
- Sujet
- Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation.
- Poids moléculaire
- 50 kDa
- NCBI Accession
- NP_003361
- UniProt
- P50552
- Pathways
- TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation
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