EIF2A anticorps (pSer49)
-
- Antigène Voir toutes EIF2A Anticorps
- EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))
-
Épitope
- pSer49
-
Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp EIF2A est non-conjugé
-
Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Specificité
- The antibody detects endogenous level of eIF2a only when phosphorylated at Serine 49.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Immunogène
- Peptide sequence around phosphorylation site of pSer49 (L-L-S (p) -E-L) derived from Human eIF2a. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Isotype
- IgG
- Top Product
- Discover our top product EIF2A Anticorps primaire
-
-
- Indications d'application
-
Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
-
- Antigène
- EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))
- Autre désignation
- eIF2alpha (EIF2A Produits)
- Synonymes
- anticorps ATEIF2-A2, anticorps EIF2-A2, anticorps eukaryotic translation initiation factor 2 alpha subunit, anticorps EIF-2A, anticorps MST089, anticorps MSTP004, anticorps MSTP089, anticorps D030048D22, anticorps D3Ertd194e, anticorps im:7145971, anticorps zgc:110460, anticorps DDBDRAFT_0185936, anticorps DDBDRAFT_0234177, anticorps DDB_0185936, anticorps DDB_0234177, anticorps Eif2a, anticorps eif2a, anticorps eif2alpha, anticorps EIF2A, anticorps CG9946, anticorps Dmel\\CG9946, anticorps Eif2alpha, anticorps IF2A_DROME, anticorps M(1)14C, anticorps M(1)19-153, anticorps M(1)8e3-10, anticorps deIF2alpha, anticorps eIF-2, anticorps eIF-2 a, anticorps eIF-2 alpha, anticorps eIF2 alpha, anticorps eIF2-alpha, anticorps eIF2a, anticorps eIF2alpha, anticorps eiF-2alpha, anticorps elF2alpha, anticorps l(1)14Cf, anticorps l(1)19-153, anticorps eukaryotic translation initiation factor 2 alpha subunit, anticorps eukaryotic translation initiation factor 2A, anticorps eukaryotic translation initiation factor 2A, 65kDa, anticorps eukaryotic translation initiation factor 2A S homeolog, anticorps eukaryotic translation initiation factor, anticorps eukaryotic translation Initiation Factor 2alpha, anticorps EIF2 ALPHA, anticorps EIF2A, anticorps Eif2a, anticorps eif2a, anticorps eIF2a, anticorps eif2a.S, anticorps eif2A, anticorps eIF-2alpha
- Sujet
- Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
- Poids moléculaire
- 38 kDa
- NCBI Accession
- NP_004085
- UniProt
- P05198
- Pathways
- Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C, Methionine Biosynthetic Process, Ribosome Assembly
-