Paxillin anticorps (pTyr88)
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- Antigène Voir toutes Paxillin (PXN) Anticorps
- Paxillin (PXN)
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Épitope
- pTyr88
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Paxillin est non-conjugé
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Application
- Immunofluorescence (IF)
- Specificité
- The antibody detects endogenous level of Paxillin only when phosphorylated at tyrosine 88.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Immunogène
- Peptide sequence around phosphorylation site of pTyr88 (P-V-Y (p) -G-S) derived from Human Paxillin. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Isotype
- IgG
- Top Product
- Discover our top product PXN Anticorps primaire
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- Indications d'application
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Western blotting: 1:500-1:1000
Immunofluorescence: 1:100-1:200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Antigène
- Paxillin (PXN)
- Autre désignation
- Paxillin (PXN Produits)
- Synonymes
- anticorps AW108311, anticorps AW123232, anticorps Pax, anticorps CG18061, anticorps CG18576, anticorps CG31794, anticorps CT40481, anticorps CT42454, anticorps DPaxillin, anticorps DPxn, anticorps DPxn37, anticorps Dmel\\CG31794, anticorps Dpax, anticorps DpaxA, anticorps PDLP, anticorps dPax, anticorps pax, anticorps wu:fw71f12, anticorps PXN, anticorps LOC100220858, anticorps paxillin, anticorps Paxillin, anticorps paxillin S homeolog, anticorps paxillin a, anticorps PXN, anticorps Pxn, anticorps Pax, anticorps pxn.S, anticorps pxna, anticorps LOC696336, anticorps pxn
- Sujet
- An antiphosphotyrosine antibody was used to identify proteins that are phosphorylated in Rous sarcoma virus-transformed chick embryo fibroblasts, and a 76-kD protein was obtained that localizes to focal adhesions at the ends of actin-containing stress fibers in nontransformed cells (Ref.1). This protein was purified from chicken gizzard smooth muscle, and was named Pxn (Paxillin) ('paxillus' means 'small stake' or 'peg' in Latin) as a protein tethered to the membrane at focal adhesions
- Poids moléculaire
- 68 kDa
- NCBI Accession
- NP_001074
- UniProt
- P49023
- Pathways
- Signalisation MAPK, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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