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RAF1 anticorps (AA 257-261)
RAF1
Reactivité: Humain, Souris, Rat
WB, IHC
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-RAF1 anticorps
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Antigène
Voir toutes RAF1 Anticorps
RAF1
(V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1))
Épitope
Tous les épitopes à travers RAF1 Anticorps.
AA 257-261
Reactivité
Toutes les réactivités sur RAF1 Anticorps
Humain, Souris, Rat
Hôte
Toutes les hôtes sur RAF1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur RAF1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers RAF1 Anticorps
Cet anticorp RAF1 est non-conjugé
Application
Tous les applications à travers RAF1 Anticorps.
Western Blotting (WB), Immunohistochemistry (IHC)
Specificité
The antibody detects endogenous level of total Raf1 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogène
Peptide sequence around AA 257-261 (S-T-S-T-P) derived from Human RAF. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Isotype
IgG
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Information d'application
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Indications d'application
Western blotting: 1:500-1:1000 Immunohistochemistry: 1:50-1:100
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Références pour anticorps anti-RAF1 (ABIN362494)
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Qiu, Wang, Han, Liu, Huang, Altaf, Qiu, Javed, Zheng, Chen, Li : "Prognostic impact of Raf-1 and p-Raf-1 expressions for poor survival rate in non-small cell lung cancer. " dans: Cancer science , Vol. 103 , Issue 10 , pp. 1774-9 , (2012 ) (PubMed ).
Détails sur RAF1
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Antigène
RAF1
(V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1))
Autre désignation
Raf1 (RAF1 Produits )
Synonymes
anticorps CRAF, anticorps NS5, anticorps Raf-1, anticorps c-Raf, anticorps c-raf, anticorps craf, anticorps raf1, anticorps RAF1, anticorps 6430402F14Rik, anticorps AA990557, anticorps BB129353, anticorps Craf1, anticorps D830050J10Rik, anticorps v-Raf, anticorps raf, anticorps cRaf, anticorps Raf-1 proto-oncogene, serine/threonine kinase, anticorps Raf-1 proto-oncogene, serine/threonine kinase a, anticorps v-raf-leukemia viral oncogene 1, anticorps Raf-1 proto-oncogene, serine/threonine kinase S homeolog, anticorps RAF1, anticorps Raf1, anticorps raf1a, anticorps raf1, anticorps raf1.S
Sujet
Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3.
Poids moléculaire
73 kDa
UniProt
P04049
Pathways
Signalisation MAPK , Signalisation RTK , Fc-epsilon Receptor Signaling Pathway , Neurotrophin Signaling Pathway , cAMP Metabolic Process , Stem Cell Maintenance , Hepatitis C , Autophagy , Signaling of Hepatocyte Growth Factor Receptor , VEGF Signaling , BCR Signaling
Vus récemment
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