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STAT3 anticorps (AA 725-729)
STAT3
Reactivité: Humain, Souris, Rat
WB, IHC
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-STAT3 anticorps
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Antigène
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STAT3
(Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))
Épitope
Tous les épitopes à travers STAT3 Anticorps.
AA 725-729
Reactivité
Toutes les réactivités sur STAT3 Anticorps
Humain, Souris, Rat
Hôte
Toutes les hôtes sur STAT3 Anticorps
Lapin
Clonalité
Toutes les clonalités sur STAT3 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers STAT3 Anticorps
Cet anticorp STAT3 est non-conjugé
Application
Tous les applications à travers STAT3 Anticorps.
Western Blotting (WB), Immunohistochemistry (IHC)
Specificité
The antibody detects endogenous level of total STAT3 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogène
Peptide sequence around AA 725-729 (P-M-S-P-R) derived from Human STAT3. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Isotype
IgG
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Information d'application
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Indications d'application
Western blotting: 1:500-1:1000 Immunohistochemistry: 1:50-1:100
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Références pour anticorps anti-STAT3 (ABIN362567)
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Cheng, Wang, Xia, Yan, Tang, Chen, Zhang, Liu, Kong, Sjöberg, Folco, Libby, Liao, Shi : "A guanidine-rich regulatory oligodeoxynucleotide improves type-2 diabetes in obese mice by blocking T-cell differentiation. " dans: EMBO molecular medicine , Vol. 4 , Issue 10 , pp. 1112-25 , (2012 ) (PubMed ).
Yu, Qin, He, Wang, Fu, Liu, Guo, Liang, Dou, Han : "Canonical notch pathway protects hepatocytes from ischemia/reperfusion injury in mice by repressing reactive oxygen species production through JAK2/STAT3 signaling. " dans: Hepatology (Baltimore, Md.) , Vol. 54 , Issue 3 , pp. 979-88 , (2011 ) (PubMed ).
Détails sur STAT3
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Antigène
STAT3
(Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))
Autre désignation
STAT3 (STAT3 Produits )
Synonymes
anticorps 1110034C02Rik, anticorps AW109958, anticorps Aprf, anticorps APRF, anticorps HIES, anticorps Xstat3, anticorps aprf, anticorps hies, anticorps stat3, anticorps wu:fc15d02, anticorps wu:fl59g06, anticorps z-Stat3, anticorps signal transducer and activator of transcription 3, anticorps signal transduction and activation of transcription 3, anticorps signal transducer and activator of transcription 3, gene 1 L homeolog, anticorps signal transducer and activator of transcription 3 (acute-phase response factor), anticorps STAT3, anticorps stat3, anticorps Stat3, anticorps stat3.1.L
Sujet
Transcription factor that binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes.
Poids moléculaire
88 kDa
NCBI Accession
NP_003141
UniProt
P40763
Pathways
Signalistation JAK/STAT , Signalisation RTK , Interferon-gamma Pathway , Neurotrophin Signaling Pathway , Dopaminergic Neurogenesis , Response to Growth Hormone Stimulus , Carbohydrate Homeostasis , Stem Cell Maintenance , Hepatitis C , Protein targeting to Nucleus , Feeding Behaviour , CXCR4-mediated Signaling Events , Signaling of Hepatocyte Growth Factor Receptor
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