×
Pour une meilleure utilisation, nous vous conseillons d’activer Javascript dans votre navigateur.
Src anticorps (AA 527-531)
Src
Reactivité: Humain, Souris, Rat
WB, IHC
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-Src anticorps
(cache)
Antigène
Voir toutes Src Anticorps
Src
(Proto-oncogene tyrosine-protein kinase Src (Src))
Épitope
Tous les épitopes à travers Src Anticorps.
AA 527-531
Reactivité
Toutes les réactivités sur Src Anticorps
Humain, Souris, Rat
Hôte
Toutes les hôtes sur Src Anticorps
Lapin
Clonalité
Toutes les clonalités sur Src Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers Src Anticorps
Cet anticorp Src est non-conjugé
Application
Tous les applications à travers Src Anticorps.
Western Blotting (WB), Immunohistochemistry (IHC)
Specificité
The antibody detects endogenous level of total Src protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogène
Peptide sequence around AA 527-531 (P-Q-Y-Q-P) derived from Human Src. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Isotype
IgG
Top Product
Discover our top product Src Anticorps primaire
Alternatives
(show)
Information d'application
(cache)
Indications d'application
Western blotting: 1:500-1:1000 Immunohistochemistry: 1:50-1:100
Restrictions
For Research Use only
Stockage
(cache)
Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Références pour anticorps anti-Src (ABIN362786)
(cache)
Zheng, Xia, Hawke, Halle, Tremblay, Gao, Zhou, Aldape, Cobb, Xie, He, Lu : "FAK phosphorylation by ERK primes ras-induced tyrosine dephosphorylation of FAK mediated by PIN1 and PTP-PEST. " dans: Molecular cell , Vol. 35 , Issue 1 , pp. 11-25 , (2009 ) (PubMed ).
Détails sur Src
(cache)
Antigène
Src
(Proto-oncogene tyrosine-protein kinase Src (Src))
Autre désignation
Src (Src Produits )
Synonymes
anticorps AW259666, anticorps pp60c-src, anticorps C-src1, anticorps CG7524, anticorps D-Src64B, anticorps D-src, anticorps DSRC64, anticorps DSrc, anticorps DSrc64, anticorps DSrc64B, anticorps Dm SRC1, anticorps DmHD-358, anticorps Dmel\CG7524, anticorps Dsrc, anticorps Dsrc64, anticorps Dsrc64B, anticorps HD-358, anticorps MRE5, anticorps SRC 64B, anticorps Src, anticorps Src1, anticorps Src64, anticorps c-src, anticorps dSrc, anticorps dsrc, anticorps src, anticorps src1, anticorps src64, anticorps src64B, anticorps src64b, anticorps ASV, anticorps SRC1, anticorps c-SRC, anticorps p60-Src, anticorps c-Src, anticorps PP60C-SCR, anticorps SDR, anticorps SRC proto-oncogene, non-receptor tyrosine kinase, anticorps uncharacterized LOC5574802, anticorps proto-oncogene tyrosine-protein kinase src, anticorps Rous sarcoma oncogene, anticorps Src oncogene at 64B, anticorps SRC, anticorps LOC5574802, anticorps CpipJ_CPIJ010659, anticorps Src, anticorps Src64B
Classe de substances
Viral Protein
Sujet
Proto-oncogenic cytoplasmic tyrosine kinase of the SRC family. Highly expressed in certain fully differentiated cells such as neurons, platelets and macrophages. Phosphorylation of an activation loop tyrosine activates the enzyme, phosphorylation of a tyrosine in the C-terminus by Csk inhibits the enzyme.
Poids moléculaire
60 kDa
NCBI Accession
NP_005408
UniProt
P12931
Pathways
Signalistation JAK/STAT , Neurotrophin Signaling Pathway , Intracellular Steroid Hormone Receptor Signaling Pathway , Regulation of Intracellular Steroid Hormone Receptor Signaling , Cellular Response to Molecule of Bacterial Origin , Cell-Cell Junction Organization , Regulation of Carbohydrate Metabolic Process , Autophagy , CXCR4-mediated Signaling Events , Signaling Events mediated by VEGFR1 and VEGFR2 , Smooth Muscle Cell Migration , Negative Regulation of intrinsic apoptotic Signaling , Platelet-derived growth Factor Receptor Signaling , Thromboxane A2 Receptor Signaling , Signaling of Hepatocyte Growth Factor Receptor , VEGF Signaling
Vus récemment
(cache)