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PRKDC anticorps (AA 2607-2611)
PRKDC
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-PRKDC anticorps
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Antigène
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PRKDC
(Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
Épitope
Tous les épitopes à travers PRKDC Anticorps.
AA 2607-2611
Reactivité
Toutes les réactivités sur PRKDC Anticorps
Humain
Hôte
Toutes les hôtes sur PRKDC Anticorps
Lapin
Clonalité
Toutes les clonalités sur PRKDC Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers PRKDC Anticorps
Cet anticorp PRKDC est non-conjugé
Application
Tous les applications à travers PRKDC Anticorps.
Western Blotting (WB)
Specificité
The antibody detects endogenous level of total DNA PKcs protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogène
Peptide sequence around AA 2607-2611 (V-E-T-Q-A) derived from Human DNA-PK. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Isotype
IgG
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Information d'application
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Indications d'application
Western blotting: 1:500-1:1000
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Détails sur PRKDC
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Antigène
PRKDC
(Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
Autre désignation
DNA PKcs (PRKDC Produits )
Synonymes
anticorps DNA-PKcs, anticorps DNAPK, anticorps DNPK1, anticorps HYRC, anticorps HYRC1, anticorps XRCC7, anticorps p350, anticorps DNA-PKCS, anticorps dna-pkcs, anticorps dnapk, anticorps dnpk1, anticorps hyrc, anticorps hyrc1, anticorps prkdc-A, anticorps xrcc7, anticorps PRKDC, anticorps AI326420, anticorps AU019811, anticorps DNAPDcs, anticorps DOXNPH, anticorps dxnph, anticorps p460, anticorps scid, anticorps slip, anticorps protein kinase, DNA-activated, catalytic polypeptide, anticorps protein kinase, DNA-activated, catalytic polypeptide L homeolog, anticorps DNA-dependent protein kinase catalytic subunit, anticorps protein kinase, DNA activated, catalytic polypeptide, anticorps PRKDC, anticorps prkdc.L, anticorps LOC100633457, anticorps Prkdc
Sujet
The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity, PRKDC must be bound to DNA to express its catalytic properties
Poids moléculaire
450 kDa
NCBI Accession
NP_001075
UniProt
P78527
Pathways
Réparation de l'ADN , Production of Molecular Mediator of Immune Response
Vus récemment
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