APP anticorps (AA 666-670)
-
- Antigène Voir toutes APP Anticorps
- APP (Amyloid beta (A4) Precursor Protein (APP))
-
Épitope
- AA 666-670
-
Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp APP est non-conjugé
-
Application
- Western Blotting (WB), Immunofluorescence (IF)
- Specificité
- The antibody detects endogenous level of total APP protein.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
- Immunogène
- Peptide sequence around AA 666-670 (A-V-T-P-E ) derived from Human APP. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
- Isotype
- IgG
- Top Product
- Discover our top product APP Anticorps primaire
-
-
- Indications d'application
-
Western blotting: 1:500-1:1000
Immunofluorescence: 1:100-1:200 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
-
- Antigène
- APP (Amyloid beta (A4) Precursor Protein (APP))
- Autre désignation
- APP (APP Produits)
- Synonymes
- anticorps AAA, anticorps ABETA, anticorps ABPP, anticorps AD1, anticorps APPI, anticorps CTFgamma, anticorps CVAP, anticorps PN-II, anticorps PN2, anticorps aaa, anticorps abeta, anticorps abpp, anticorps ad1, anticorps appi, anticorps ctfgamma, anticorps cvap, anticorps pn2, anticorps APP, anticorps APP-like, anticorps APPL, anticorps Abeta, anticorps BcDNA:GH04413, anticorps CG7727, anticorps Dmel\\CG7727, anticorps EG:65F1.5, anticorps appl, anticorps Abpp, anticorps Adap, anticorps Ag, anticorps Cvap, anticorps E030013M08Rik, anticorps betaApp, anticorps app, anticorps wu:fj34d10, anticorps wu:fk65e12, anticorps zgc:85740, anticorps amyloid beta precursor protein, anticorps amyloid beta (A4) precursor protein, anticorps beta amyloid protein precursor-like, anticorps amyloid beta (A4) precursor protein a, anticorps amyloid beta precursor protein L homeolog, anticorps APP, anticorps app, anticorps Appl, anticorps App, anticorps appa, anticorps app.L
- Sujet
- APP encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
- Poids moléculaire
- 100-140 kDa
- NCBI Accession
- NP_000475
- UniProt
- P05067
- Pathways
- Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour
-